CLIPPERS syndrome

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Effective antituberculous therapy in a patient with CLIPPERS: New insights into CLIPPERS pathogenesis

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a brainstem relapsing-remitting inflammatory disease. To date, no treatment besides corticosteroids has been shown to be effective to treat relapses. We report a patient with CLIPPERS initially misdiagnosed with CNS tuberculosis who presented with brainstem attacks responsive to antituber...

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Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI

OBJECTIVE To examine if there is widespread inflammation in the brain of patients with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome by using histology and ultra-high-field MRI at 7.0T. METHODS We performed a detailed neuropathologic examination in 4 cases, including 1 autopsy case, and studied 2 additional patients by MRI at...

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Expanding phenotype of CLIPPERS indicates it to be a disease or a syndrome?

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ژورنال

عنوان ژورنال: Neurology, Neuropsychiatry, Psychosomatics

سال: 2018

ISSN: 2310-1342,2074-2711

DOI: 10.14412/2074-2711-2018-2-76-82